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Both Neglected Diseases |


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Human African Trypanosomiasis:
Over 60 million people are at risk of contracting Human African Trypanosomiasis and there are about 300,000 currently infected patients. A severely neglected disease according to WHO criteria, Human African Trypanosomiasis typically affects poor rural populations that live in the endemic areas from 36 sub-Saharan African countries, generally far away from primary health facilities.
Human African Trypanosomiasis or sleeping sickness is an infectious disease caused by two subspecies of the Trypanosoma brucei parasite that is transmitted to humans by the tsetse fly.
Human African Trypanosomiasis patients present symptoms from fever, headache and joint pains to neurological, sensorial and motor dysfunction, the circadian cycle alteration being the most important symptom. They inevitably die without treatment after a prolonged period of grave illness.
Leishmaniasis:
This other neglected disease is encountered world-wide in 88 countries in tropical and sub-tropical regions and threatens 350 million people with 12 million infected persons. The disease is endemic in Europe and in several countries of Asia and North and East Africa. The situation is expected to worsen through human-made and environmental changes, HIV-Leishmania co-infection and resistance to drugs.
Leishmaniasis is caused by several species of the Leishmania parasite that is transmitted to humans by sand flies.
It is characterised by a spectrum of clinical manifestations ranging from mild cutaneous lesions, to disfiguring lesions or lethal visceral forms depending on the parasite species. |
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Human African Trypanosomiasis And Leishmaniasis Diagnostics |
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TRYLEIDIAG Network |

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